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1996-02-26
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Document 0432
DOCN M9620432
TI The changing spectrum of pulmonary infections due to nontuberculous
mycobacteria.
DT 9602
AU Boggs DS; University of Oklahoma Health Sciences Center, Division of;
Pulmonary and Critical Care Medicine, Oklahoma City, USA.
SO J Okla State Med Assoc. 1995 Sep;88(9):373-82. Unique Identifier :
AIDSLINE MED/96033393
AB Although nontuberculous mycobacteria (NTM) infections are not common,
there is evidence that they are becoming increasingly recognized and in
some parts of the country occur more frequently than M. tuberculosis.
The classic description of NTM pulmonary infection is that of a male
patient with cavitary infiltrates and predisposing lung disease. With an
increase in the number of reported cases of infection, there have been
other syndromes described, particularly in elderly female patients
without any predisposing conditions, those with asymptomatic pulmonary
nodules, esophageal disease causing recurrent aspiration pneumonitis,
and disseminated infection in AIDS. Therapy of M. avium complex (MAC)
disease is far from definitive whereas infections due to M. kansasii can
be effectively treated even in the presence of profound
immunosuppression. Recognition of these infections and their recent
change in epidemiology hopefully will encourage practitioners to enroll
their patients into clinical protocols that will help to establish the
optimal regimen(s).
DE Causality Esophageal Diseases/MICROBIOLOGY Female Human Incidence
Lung Diseases/COMPLICATIONS/DIAGNOSIS/DRUG THERAPY/EPIDEMIOLOGY/
*MICROBIOLOGY Male Mycobacterium avium Complex *Mycobacterium
Infections, Atypical/COMPLICATIONS/DIAGNOSIS/DRUG THERAPY/EPIDEMIOLOGY
Mycobacterium, Atypical/ISOLATION & PURIF JOURNAL ARTICLE REVIEW
REVIEW LITERATURE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).