home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Collection of Education
/
collectionofeducationcarat1997.iso
/
HEALTH
/
MED9602.ZIP
/
M9620446.TXT
< prev
next >
Wrap
Text File
|
1996-02-26
|
2KB
|
36 lines
Document 0446
DOCN M9620446
TI [MRI aspects of progressive multifocal leukoencephalopathy]
DT 9602
AU Sarrazin JL; Soulie D; Derosier C; Lescop J; Schill H; Cordoliani YS;
H.I.A du Val-de-Grace, Paris.
SO J Neuroradiol. 1995 Sep;22(3):172-9. Unique Identifier : AIDSLINE
MED/96043312
AB Progressive Multifocal Leukoencephalopathy is a demyelinating disease.
MRI shows high signal intensity areas on T2w sequence and low intensity
aeras on T1w sequence, without enhancement after intravenous contrast
injection. The involvement of arcuate fiber (U fibers) creates a sharp
border with the cortex. There is no mass effect. Involvement of
parieto-occipital areas is frequent. The lesions may be uni or
bilateral, single or multiple; bilateral lesions are asymmetric. This
typical appearance on MR images occurs in 90% of the patients with PML.
Some atypical patterns may occur: focal hemorrhage, atrophy, faint
peripheral enhancement and involvement of deep gray matter (basal
ganglia). In most cases, the clinical and MR features provide the
diagnosis. The main differential diagnosis, in MRI, is
HIV-leukoencephalitis, but lesions are diffuse, less intense on T2w
sequence and not visible on T1, without involvement of the arcuate
fibers. Stereotactic biopsy should be performed only for atypical
lesions, particularly in case of predominant involvement of deep gray
structures.
DE Arcuate Nucleus/PATHOLOGY Atrophy AIDS Dementia Complex/DIAGNOSIS
Biopsy Cerebral Cortex/PATHOLOGY Cerebral Hemorrhage/DIAGNOSIS
Contrast Media Diagnosis, Differential English Abstract Human
Leukoencephalopathy, Progressive Multifocal/*DIAGNOSIS *Magnetic
Resonance Imaging Stereotaxic Techniques JOURNAL ARTICLE REVIEW
REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).