home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Collection of Education
/
collectionofeducationcarat1997.iso
/
HEALTH
/
MED9602.ZIP
/
M9620685.TXT
< prev
next >
Wrap
Text File
|
1996-02-26
|
2KB
|
34 lines
Document 0685
DOCN M9620685
TI [Use of parenteral nutritional support in patients with gastric cancer:
the relationship of protein turn over, immunocompetence and tumor cell
kinetics]
DT 9602
AU Cao W; Lin Y; Yin H; Ruijin Hospital, Shanghai Second Medical
University.
SO Chung Hua Wai Ko Tsa Chih. 1995 May;33(5):265-8. Unique Identifier :
AIDSLINE MED/96041504
AB In order to elucidate the effect of preoperative parenteral nutritional
support (PNS) on protein metabolism, host immunocompetence and tumor
cell kinetics, two prospective trials were made in patients with gastric
cancer. All the patients were given PNS for 7 days in addition to oral
intake. The positive nitrogen balance and increase of protein anabolic
rate was greater in PNS groups than in control group. There was a
moderate increase in NKC after PNS. The rise in CD4+ was significant (P
< 0.05). The percentage of G0/G1 cells fell after PNS (P < 0.01), while
that of the whole proliferative phase (S + G2 + M) rose (P < 0.05).
These changes were not noted in normal gastric mucosa. In conclusion,
despite of stimulating tumor cell proliferation, PNS helps to promote
whole body protein synthesis and to amelio-rate the immunocompetence of
advanced gastric cancer patients before operation.
DE Adult Aged Cell Cycle CD4-CD8 Ratio English Abstract Female Human
*Immunocompetence Killer Cells, Natural/IMMUNOLOGY Male Middle Age
*Parenteral Nutrition Prealbumin/METABOLISM Preoperative Care
Prospective Studies Stomach Neoplasms/BLOOD/PATHOLOGY/*THERAPY
Transferrin/METABOLISM CLINICAL TRIAL JOURNAL ARTICLE RANDOMIZED
CONTROLLED TRIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).