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1996-02-26
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Document 0931
DOCN M9620931
TI Abnormalities of visual spatial attention in HIV infection and the
HIV-associated dementia complex.
DT 9602
AU Maruff P; Malone V; McArthur-Jackson C; Mulhall B; Benson E; Currie J;
Neurophysiology and Neurovisual Research Unit, Mental Health; Research
Institute of Victoria, Parkville, Australia.
SO J Neuropsychiatry Clin Neurosci. 1995 Summer;7(3):325-33. Unique
Identifier : AIDSLINE MED/96076004
AB Covert orienting of visuospatial attention (COVAT) was examined in 88
homosexual or bisexual men: 12 with mild HIV-associated dementia complex
(ADC), 30 neurologically intact with AIDS (NI-AIDS), 23 asymptomatic
HIV+ (HIV+ASX), and 23 HIV-negative control subjects. In mild ADC, COVAT
was normal for spatial but impaired for nonspatial cues; 17% of NI-AIDS
and HIV+ASX subjects had similar COVAT impairment patterns and also
showed cognitive deficits. HIV+ subjects with normal COVAT showed normal
cognitive performance. Impairment of nonspatial attentional processing
in the ADC subjects and subgroups of the neurologically intact HIV+
subjects may reflect early subcortical dysfunction caused by HIV
infection. COVAT assessment may be sensitive for detection of early
subclinical neurological impairment in HIV infection.
DE Adult Affect Age Factors Attention/*PHYSIOLOGY AIDS Dementia
Complex/*PSYCHOLOGY Human HIV Infections/*PSYCHOLOGY Male
Neuropsychological Tests Orientation/PHYSIOLOGY Psychometrics
Reaction Time/PHYSIOLOGY Space Perception/*PHYSIOLOGY Visual
Perception/*PHYSIOLOGY CLINICAL TRIAL JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).