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1996-02-26
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Document 1057
DOCN M9621057
TI Dual seroreactivity to HIV-1 and HIV-2 in female sex workers in Abidjan,
Cote d'Ivoire.
DT 9602
AU Ghys PD; Diallo MO; Ettiegne-Traore V; Yeboue KM; Gnaore E; Lorougnon F;
Teurquetil MJ; Adom ML; Greenberg AE; Laga M; et al; Projet RETRO-CI,
Abidjan, Cote d'Ivoire.
SO AIDS. 1995 Aug;9(8):955-8. Unique Identifier : AIDSLINE MED/96014972
AB OBJECTIVE: To determine the absolute and proportional prevalence of dual
seroreactivity to HIV-1 and HIV-2 in female sex workers in Abidjan, to
determine risk determinants for this serologic profile, and to describe
the associated clinical and immunological characteristics. DESIGN:
Cross-sectional study. SETTING: Confidential clinic for female sex
workers in Abidjan. PARTICIPANTS: Female sex workers. MAIN OUTCOME
MEASURES: HIV serostatus, CD4+ counts, women with AIDS, behavioural and
sociodemographic characteristics. RESULTS: Among 1209 women tested, the
overall HIV seroprevalence was 80%, while the prevalence of dual
seroreactivity was 30%. Dual seroreactivity accounted for 38% of all HIV
infections. Compared with women reacting to HIV-1 only, dually
seroreactive women were significantly more likely to have been in sex
work for a longer period, to be aged > or = 20 years, and to charge less
money for intercourse. No difference in mean CD4+ count was noted
between women with dual seroreactivity (561 x 10(6)/l) and
HIV-1-seropositive women (558 x 10(6)/l). CONCLUSIONS: Female sex
workers in Abidjan had the highest absolute (30%) and proportional rate
(38%) of dual seroreactivity yet described in any population. Increased
sexual exposure is associated with an increased risk of dual
seroreactivity. Although better molecular diagnostic techniques are
required, a substantial proportion of female sex workers in Abidjan is
likely to be infected with both HIV-1 and HIV-2.
DE Adult Cote d'Ivoire/EPIDEMIOLOGY Cross-Sectional Studies Female
Human HIV Infections/*EPIDEMIOLOGY *HIV Seroprevalence *HIV-1 *HIV-2
*Prostitution Risk Factors Support, Non-U.S. Gov't Support, U.S.
Gov't, Non-P.H.S. JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).