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M9650982.TXT
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1996-03-30
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Document 0982
DOCN M9650982
TI Effect of formaldehyde fixation on some mechanical properties of bovine
bone.
DT 9505
AU Currey JD; Brear K; Zioupos P; Reilly GC; Department of Biology,
University of York, UK.
SO Biomaterials. 1995 Nov;16(16):1267-71. Unique Identifier : AIDSLINE
MED/96113654
AB The risk of infection of investigators working on the biomechanics of
human bone from a variety of modern pathogens including the human
immunodeficiency virus or the hepatitis B virus has increased recently.
New safety procedures are needed to reduce that risk. The procedure we
follow in our laboratory employs brief (< 3 h) fixation in formaldehyde,
and we report here the effects it has on some mechanical properties of
bovine bone. Results in quasistatic loading tests were almost unaffected
by our fixation protocol, but a significant decrease in impact strength
was found. These results indicate that there may be some interaction
between fixation and strain rate dependent effects and, therefore, some
caution is needed when using common biomechanical measurement methods on
fixed bone material.
DE Animal Biomechanics Bone and Bones/*DRUG EFFECTS/*PHYSIOLOGY/VIROLOGY
Cattle Fixatives/*PHARMACOLOGY Formaldehyde/*PHARMACOLOGY Human In
Vitro Materials Testing Safety Stress, Mechanical Support, Non-U.S.
Gov't Tensile Strength Tissue Fixation Virus Diseases/TRANSMISSION
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).