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1996-03-30
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Document 0990
DOCN M9650990
TI Chronic diarrhea among adults in Kigali, Rwanda: association with
bacterial enteropathogens, rectocolonic inflammation, and human
immunodeficiency virus infection.
DT 9505
AU Clerinx J; Bogaerts J; Taelman H; Habyarimana JB; Nyirabareja A;
Ngendahayo P; Van de Perre P; Centre Hospitalier de Kigali (Departments
of Internal Medicine,; Microbiology, and Pathology), Rwanda.
SO Clin Infect Dis. 1995 Nov;21(5):1282-4. Unique Identifier : AIDSLINE
MED/96126016
AB One hundred patients with chronic diarrhea were seen in the Department
of Internal Medicine at the Centre Hospitalier de Kigali, Rwanda; stool
and/or rectal swab culture was performed for these patients, and they
underwent rectoscopy and serological testing for human immunodeficiency
virus type 1 (HIV-1). Enteropathogenic bacteria were isolated from 39
(39%) of the patients: Shigella species (22 of 100 patients tested),
non-typhi Salmonella (11/100), Aeromonas species (5/60), and
Campylobacter species (4/60). Rectocolitis was seen in 70 (70%) of the
patients. HIV-1 antibodies were detected in 82 (94%) of 87 patients
tested. Cytomegalovirus was not found in rectal biopsy specimens from 29
patients. Entamoeba histolytica was detected in two of 31 rectal smears.
Idiopathic ulcerative colitis was diagnosed for two HIV-1-seropositive
patients. One or more AIDS-defining diseases were found in 32 (32%) of
the patients, and 72 (72%) fulfilled the World Health Organization's
clinical case definition criteria for AIDS. Chronic diarrhea, as seen in
a hospital setting in a region highly endemic for HIV-1 infection, is
strongly associated with HIV-1 infection, with rectocolonic
inflammation, and with infection due to enteropathogenic bacteria.
DE Adult Chronic Disease Colitis/COMPLICATIONS/EPIDEMIOLOGY
Diarrhea/*COMPLICATIONS/EPIDEMIOLOGY Enterobacteriaceae
Infections/COMPLICATIONS/EPIDEMIOLOGY Female Human HIV
Infections/*COMPLICATIONS/EPIDEMIOLOGY *HIV-1 Male
Proctitis/COMPLICATIONS/EPIDEMIOLOGY Rwanda/EPIDEMIOLOGY Support,
Non-U.S. Gov't JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).