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M9620206.TXT
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1996-02-26
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Document 0206
DOCN M9620206
TI Why disease due to Mycobacterium tuberculosis is less common than
expected in HIV-positive patients in Edinburgh.
DT 9602
AU Leitch AG; Rubilar M; Watt B; Laing R; Willcocks L; Brettle RP; Leen CL;
Respiratory Medicine, Department of Medicine (RIE), University of;
Edinburgh, U.K.
SO Respir Med. 1995 Aug;89(7):495-7. Unique Identifier : AIDSLINE
MED/96048169
AB By December 1993, only five cases of tuberculosis were observed in the
1030 HIV-positive patients in Edinburgh, U.K., although, on the basis of
historical tuberculin skin test data, between four and eight new cases
of tuberculosis were expected per year. Of 310 HIV-positive patients,
none of the 19 (6.1%) who were tuberculin skin test positive had
developed tuberculosis after 87 months (average) of follow-up. It is
suggested that new or re-infection is a more common cause of
tuberculosis in HIV-positive patients than reactivation. Restriction
fragment length polymorphism typing of Mycobacterium tuberculosis
strains could confirm this hypothesis and support currently suggested
additional infection control procedures.
DE Adult Follow-Up Studies Human HIV Infections/*COMPLICATIONS Male
Recurrence Scotland/EPIDEMIOLOGY Tuberculin Test
Tuberculosis/COMPLICATIONS/*EPIDEMIOLOGY/MICROBIOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).